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A total of three % of Lively substance is excreted in urine as unchanged active compound. Tapentadol is Furthermore metabolised to N-desmethyl tapentadol (thirteen %) by CYP2C9 and CYP2C19 and to hydroxy tapentadol (two %) by CYP2D6, that happen to be more metabolised by conjugation. Consequently, Lively substance metabolism mediated by cytochrome … Read More